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Creators/Authors contains: "Hof, Fraser"

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  1. ; ; ; ; ; ; ; (, Organic & Biomolecular Chemistry)
    We report the molecular recognition properties of Pillar[ n ]MaxQ (P[ n ]MQ) toward a series of (methylated) amino acids, amino acid amides, and post-translationally modified peptides by a combination of 1 H NMR, isothermal titration calorimetry, indicator displacement assays, and molecular dynamics simulations. We find that P6MQ is a potent receptor for N -methylated amino acid side chains. P6MQ recognized the H3K4Me 3 peptide with K d = 16 nM in phosphate buffered saline. 
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  2. ; ; ; ; (, Journal of the American Chemical Society)
  3. ; ; ; ; ; ; (, ChemBioChem)